Package: pkident 0.1.0

pkident: Structural and Practical Identifiability for Pharmacokinetic and Pharmacodynamic Models

Determines which parameters of pharmacokinetic and pharmacodynamic ordinary differential equation models can be identified from a given dosing and observation design, and which added measurement would make the others identifiable. Decisions are local and are stated as such.

Authors:Daiki Kumakura [aut, cre]

pkident_0.1.0.tar.gz
pkident_0.1.0.zip(r-4.7-any)pkident_0.1.0.zip(r-4.6-any)pkident_0.1.0.zip(r-4.5-any)
pkident_0.1.0.tgz(r-4.6-any)pkident_0.1.0.tgz(r-4.5-any)
pkident_0.1.0.tar.gz(r-4.7-any)pkident_0.1.0.tar.gz(r-4.6-any)
pkident_0.1.0.tgz(r-4.6-emscripten)
manual.pdf |manual.html✨
DESCRIPTION |NEWS
card.svg |card.png
pkident/json (API)

# Install 'pkident' in R:
install.packages('pkident', repos = c('https://daikikumakura.r-universe.dev', 'https://cloud.r-project.org'))

Bug tracker:https://github.com/daikikumakura/pkident/issues

On CRAN:

Conda:

identifiabilitynlmixr2pharmacokineticspharmacometricspkpdrxode2

3.65 score 12 exports 53 dependencies

Last updated from:b0b8f5354e. Checks:9 OK. Indexed: yes.

TargetResultTimeFilesSyslog
linux-develOK193
source / vignettesOK415
linux-releaseOK187
macos-releaseOK191
macos-oldrelOK168
windows-develOK201
windows-releaseOK154
windows-oldrelOK198
wasm-releaseOK120

Exports:as_tablebolus_doseclassify_profilescompare_designsexperimentinfusion_dosepkpd_modelpractical_identifiabilityreference_modelreference_modelsresidual_errorstructural_identifiability

Dependencies:armadillo4rbackportsBHcachemcheckmateclicpp11cpp4rcrayondata.tabledigestdparserfarverfastmapggplot2gluegtableinlineisobandlabelinglifecyclelotrimagrittrmemoisemirainanonextpillarpkgconfigPreciseSumsqs2R6RColorBrewerRcppRcppArmadilloRcppEigenRcppParallelrexrlangrxode2rxode2lincmtrxode2llS7scalessitmoStanHeadersstringfishsymenginesystibbleutf8vctrsviridisLitewithr

Case study: how long must PSA be followed to estimate regrowth?
Structure | Length of observation | Do the expected RSEs hold?

Last update: 2026-10-05
Started: 2026-10-05

Case study: nimotuzumab target-mediated disposition
Data and model | 1. Structure is not the obstacle | 2. What these data determine | 3. Which measurement would determine the rest

Last update: 2026-10-05
Started: 2026-10-05

Structural identifiability of reference PK/PD models
A model, step by step | The acceptance set | Reading the results

Last update: 2026-10-05
Started: 2026-10-05

Readme and manuals

Help Manual

Help pageTopics
Extract result tablesas_table as_table.pkident_designs as_table.pkident_practical as_table.pkident_profiles as_table.pkident_structural
Dose specificationsbolus_dose infusion_dose
Classify likelihood profiles of an nlmixr2 fitclassify_profiles
Compare candidate designscompare_designs
One experiment of a designexperiment
Define a model for identifiability analysispkpd_model
Practical identifiability for a given designpractical_identifiability
Reference models with known identifiabilityreference_model reference_models
Residual error modelresidual_error
Structural identifiabilitystructural_identifiability